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These enzymes are widely distributed in nature, including prokaryotes and higher eukaryotes [36], with the exception of some higher plants [7]

Stabilization of uric acid mixed crystals by melamine

Retrieved June 18, 2017

Every level of protein structure, from primary to quaternary (if multimeric proteins), may be altered when proteins are exposed to oxidative attack by ROS, causing major physical changes in protein structure [48]