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H 2 O 2 reacts with ferrous iron (Fe 2+ ) in the Fenton reaction generating the highly toxic hydroxyl radical (OH) which can damage all cellular macromolecules (Imlay, 2003, 2008)

Key publications: 'GHK-Cu may Prevent Oxidative Stress in Skin' (2015, Cosmetics), 'GHK and DNA: Resetting the Human Genome to Health' (2014), 'The Human Tripeptide GHK-Cu in Prevention of Oxidative Stress and Degenerative Conditions of Aging' (2012)

Our data show that the carbon source influenced the transcriptional expression of the rhlC gene and, consequently, the predominance of mono-RLs or di-RLs in PAL05 cultures

A key point of our study is our finding of a reduction of glutathione in NTG patients, suggesting that excessive oxidative stress may contribute to optic nerve damage and RGC loss independently of high IOP in glaucoma