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Tolerability of mycophenolate mofetil in patients with systemic lupus erythematosus

[DOI] [PubMed] Utzschneider KM, Kahn SE

In acute gout, MSU crystals, liberated from tissue deposits by remodeling effects or microtrauma, stimulate inflammatory cascades that involve complement activation and assembly of the C5b-9 membrane attack complex, and release of multiple inflammatory cytokines, including IL-1 and the chemokines IL-8 (CXCL8) and GRO- (CXCL1)