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It has been shown that reduced synaptic activity induced by sensory deprivation in young, but not adult animals, produces specific reductions in the number of perisomatic inhibitory synapses on cortical excitatory cells, unmasking a regulatory role of neuronal activity in determining the density of inhibitory cell contacts in this specific cellular compartment (Jiao et al., 2006)

It was also noted that the BP from Cistus and Castanea plants possesses higher antimicrobial activity as compared with Rubus (flowering plants), which may correlated with the high content of phenolics such as hydroxycinnamic acid (50)