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Due to the distinct position of the conjugated N-terminal lipid between Cagri-CTR and Cagri-AMY 1 R, we also determined a structure of CTR-Gs in complex with an analogue of Cagri that lacked the lipid modification (CagriBB) to interrogate the contribution of the acylation to the conformation of Cagri-CTR complex

E.RaqeebA.Della CorteA.CinelliM.MontagnaniS.et al (2013)

Also, growth hormone levels drop as we get older, and there was interest in seeing if tweaking these levels might benefit older adults struggling with loss of bone and muscle mass and increases in body fat

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