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Furthermore, GPX4 deficient mice are associated with increased interstitial oedema and tubular cell death, suggesting a critical role for GPX4 in mediating renal tubular injury (132)

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(B) Fluorescence images of kidneys were obtained at 6 h, 12 h, 24 h and 48 h after tail intravenous injection into mice of DIR-labelled exosomes derived from TCMK-1 Rights and permissions Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material

Nature 470 (7334), 359365