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As in RCT, participants were mostly adults (mean age 30.455.5 years) and females (6095%) with class II obesity, except for studies conducted in China and South Korea, enrolling patients with a mean BMI ranging from 30.8 to 33 kg/m 2 53,54,62,66

Oral or sublingual formats are easier to take but may be better suited to gastrointestinal repair than tissue healing

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