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Moreover, oxidative stress causes an increase in O2 concentrations, which triggers the Haber-Weiss reaction and excessive production of the harmful hydroxyl radical (OH )

See a doctor if you have constipation and you: are not seeing improvement with treatment have bloating have stomach pain have blood in your stool have a sudden change in your stool or frequency experience unexpected weight loss feel tired most of the time are taking prescription medication such as opioids Can vitamin D cause constipation

To put it in perspective: being over 65 increases cancer risk by 10-11 times compared to younger individuals