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Research progress Support The animal experiments have achieved remarkable results: In the obese mouse model, after daily subcutaneous injection of AOD 9604 (250 g/kg) for 8 weeks, the body weight of the mice decreased by 12%, the subcutaneous fat mass decreased by 25%, and the weight of epididymal adipose tissue significantly decreased, confirming its effectiveness in fat reduction

These genes and their products are important indicators or directly involved in the structural changes necessary for the antidepressant effect

As shown in preclinical trials, they both have affected the metabolic rate of research models

PMC 1493623