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Serum was obtained from freshly drawn blood after an overnight hold at 4C and all samples were then deidentified

Among them, cathepsin B is thought to bind to NLRP3, thus activating the NLRP3 inflammasome

Nanoparticle-delivery studies have attempted to improve local delivery to inflamed colonic tissue

These cells are sensitive as a consequence of errors in end-processing and end-joining of DSB, defects in chromatin modifications that prevent efficient rejoining of DSBs, and inefficient ATM-mediated G 2 /M-checkpoints (Beucher et al, 2009) (see Chap