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They screened six differentially expressed ferroptosis-related genes (IL6, ANGPTL7, CDKN1A, AKR1C3, NOX4, and VLDLR) and constructed a random forest model based on these genes, which demonstrated strong diagnostic performance in the validation dataset, highlighting the close relationship between ferroptosis and immunity in atherosclerosis pathogenesis (61)

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By applying it to the affected joint or muscle, patients get high local drug concentration exactly at the pain site

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