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"It's that we don't have enough human data for most of the ones being marketed for anti-aging, athletic performance, etc

Biomaterials 31, 55645574

To examine whether retroductal injection of these hits preserves functional secretion, stimulated saliva secretion was evaluated 12 wks post-irradiation

Senescent-like microglia, in contrast, limit remyelination through SASP that involves the release of multiple inflammatory mediators, including CCL11, CXCL9, and CCL5, and increased expression of IL-2, leading to impaired remyelination in mouse models (Gross et al., 2025)