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doi: 10.1182/blood-2016-01-690743 120 BothwellPJKronCDWittkeEFCzerniakBNBodeBP

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First, ferritin can reprogram the immune microenvironment of tumors, and similar mechanisms may also be operative in the AML-supporting bone marrow microenvironment where various immunocompetent cells (including macrophage subsets) seem to support the leukemic cells [53,54,68,71,72,73,125]