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Moreover, combining RADA 16-I (the only reported as luminal filler for sciatic nerve repair, to our knowledge) with multiple bioactive sequences was shown to boost conduits regenerative potential with positive morphometric and functional outcomes

doi: 10.1016/j.freeradbiomed.2022.08.021 106 ZarkoviM

The concentration of serotonin can be modulated by the gut microbiome in multiple ways [230], most notably shown by altered concentration of serotonin and its metabolites in the hippocampus of germ-free animals [231]