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10.1016/j.freeradbiomed.2007.10.054 13 KrshnanL.van de WeijerM

Potential users should be aware that while preclinical safety appears excellent, the absence of extensive human clinical trials means unknown risks may exist

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Additionally, they also determined that the expression of protein kinase CPG16 increased, pointing to its importance in suppressing insulin gene expression in pancreatic beta cells under cytotoxicity (164)