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In conclusion, risk factors for kidney stones induce ferroptosis in the epithelial cells of the proximal tubules, and the chain of occurrence further accelerates the deposition and aggregation of crystals involved in kidney stone formation

They were exposed to the concentration of 100200 ppm

Romiplostim's mechanism of action is to bind to and activate the same receptors that naturally occurring TPO uses to increase platelet production

Concurrently, a decrease in OCR was shown, suggesting a decrease in the activity of the mitochondrial respiratory chain, which is consistent to our results