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Vitamin B(3) modulates mitochondrial vulnerability and prevents Glaucoma in aged mice

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Metabolism 38 , 753758 (1989)

For this purpose, activation of adaptive stress responses was investigated for DNA damage (p21), oxidative stress (SRXN1), inflammation (ICAMI), and ER stress (CHOP) using a HepG2-based GFP-reporter assay (Wink et al., 2014, 2017)