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10.1016/s0306-4530(99)00027-x 77 PontiroliA

H 2 O 2 produced by oxidative stress can bind to the cysteine 81 site of ATG4 to regulate the activity of ATG4 (Scherz-Shouval et al., 2007), then enhance autophagy and cause autophagic cell death (Koike et al., 2008)