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Similarly, in a diabetic rat model, localized fibronectin deposition within the placental labyrinth region alters the microenvironment at the maternal-fetal interface and leads to developmental abnormalities in offspring 139

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During the performed studies it was also observed that the administration of 5-reductase inhibitors (e.g., Finasteride) could have a strong impact on target markers, stressing the need of dedicated study for better characterizing steroid response to such intake

doi: 10.1371/journal.pone.0106601 [DOI] [PMC free article] [PubMed] [Google Scholar] 117.Paldor I, Madrer N, Vaknine Treidel S, Shulman D, Greenberg DS, Soreq H