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however, phytochemicals can disrupt the Nrf-2Keap1 interaction, allowing Nrf-2 to translocate into the nucleus

Zhang L, Huang Z, Xuan J, Yang L, Zhao T, Peng W (2024) Anti-Psoriatic Activity of Black, Green and White Tea Extracts from Southeastern China

Molecules 27:324

Molecular engineering and the exploration of novel mechanisms Enhancing the cellular permeability of PROTACs and circumventing efflux pump-mediated resistance are critical determinants of their in vivo efficacy