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Although certain indicators have been associated with the development of BIPN in clinical studies, genetic variations in drug response must also be taken into account

and Grant ME 1567/9-1 to A.J.M.)

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Primary ESCs were seeded into 12-well plates and cultured until they reached 6080% confluency, followed by transfection with 20 pmol STAT6 siRNAs per well using the Lipofectamine RNAiMAX reagent (Invitrogen, California, USA) in Opti-MEM (Gibco, New York, USA) according to the manufacturers instructions