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Recovery of polyphenols using pressurized hot water extraction (PHWE) from black rosehip followed by encapsulation for increased bioaccessibility and antioxidant activity

Additionally, oxidative stress and ROS can originate from xenobiotic bioactivation by prostaglandin H synthase (PHS) and lipoxygenases (LPOs) or microsomal P450s which can oxidize xenobiotics to free radical intermediates that react directly or indirectly with oxygen to produce ROS and oxidative stress [26] as in Fig (2)

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Bzioueche H, Simonyt Sjdin K, West CE, Khemis A, Rocchi S, Passeron T, et al