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Under healthy conditions, the GI tract contains a semipermeable epithelial mucosal barrier which protects against the unwanted passage of food antigens, toxins, and microorganisms from crossing directly into the bloodstream

Lynam DR, Derefinko KJ, Caspi A, Loeber R, Stouthamer-Loeber M

While aberrant ROS production can be detrimental to cellular health, ROS also serve as signaling molecules capable of regulating transcriptional events in the cell

Animal care was in compliance with the standard operating procedures (SOPs) of the Pharmacology Animal Facility and the European Convention for the Protection of Vertebrate Animals used for Experimental and Other Scientific Purposes (ETS 123)