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g , Quantification of NETs in WT and XKR8-deficient neutrophils treated with PMA (100 nM, 6 h) in the presence of BAPTA-AM (25 M) or EGTA-AM (25 M) ( n = 12)

Subsequently, CHE was shown to interact with DNA, according to multiple experiments ( Ka =(1.04 0.11)106], where the particular binding site of CHE is a continuous GC pairing sequence (5-TGGGGA-3/3-ACCCCT-5), and CHE is reported to have a specific combination character with single nucleotide bulge DNA with C and T