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A recent meta-analysis studied 13 OCT2 variants with varying frequency and its impact of metformin efficacy in a mixed ethnic cohort, among which one variant (rs316019) displayed both positive and negative effects in pharmacokinetics and pharmacodynamics of the drug (Peng et al., 2023)

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Astragaloside IV alleviates doxorubicin-induced cardiotoxicity by inhibiting cardiomyocyte pyroptosis through the SIRT1/NLRP3 pathway

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When the battery is full of energy and ready to power a device, that is the reduced form (GSH)

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