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*Correspondence: Giovanna Mantovani, [email protected] Specialty section: This article was submitted to Systems and Translational Endocrinology, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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44 In a biomechanical study using young porcine functional spine units endplate/apophysis fractures were induced with intradiscal pressurization

In an exemplary embodiment, alpha-methyl phenylalanine is substituted for the corresponding native amino acid, but in a further embodiment of the method, alpha-methyl phenylalanine does not have to correspond to the same native amino acid in which substitution occurs